KLK2 (Kallikrein related peptidase 2) هوَ بروتين يُشَفر بواسطة جين KLK2 في الإنسان.
الوظيفة
هذا القسم فارغ أوغير مكتمل، ساهم بتحريره.
الأهمية السريرية
هذا القسم فارغ أوغير مكتمل، ساهم بتحريره.
المراجع
^Diamandis, Eleftherios P.; Deperthes, David; Lundwall, Åke (Jun 2006). "Proceedings of the 1st International Symposium on Kallikreins, Lausanne, Switzerland, September 1-3 , 2005". Biol Chem. 387 (6): 635–636. doi:10.1515/BC.2006.081. PMID 16800723.
^Riegman PH, Vlietstra RJ, Klaassen P, van der Korput JA, Geurts van Kessel A, Romijn JC, Trapman J (May 1989). "The prostate-specific antigen gene and the human glandular kallikrein-1 gene are tandemly located on chromosome 19". FEBS Lett. 247 (1): 123–126. doi:10.1016/0014-5793(89)81253-0. PMID 2468530.
^Lundwall A, Band V, Blaber M, Clements JA, Courty Y, Diamandis EP, Fritz H, Lilja H, Malm J, Maltais LJ, Olsson AY, Petraki C, Scorilas A, Sotiropoulou G, Stenman UH, Stephan C, Talieri M, Yousef GM (Jun 2006). "A comprehensive nomenclature for serine proteases with homology to tissue kallikreins". Biol Chem. 387 (6): 637–641. doi:10.1515/BC.2006.082. PMID 16800724.
^"Entrez Gene: KLK2 Kallikrein-related peptidase 2". مؤرشف من الأصل في 05 ديسمبر 2010.
قراءة متعمقة
Riegman PH, Vlietstra RJ, van der Korput HA, et al. (1992). "Identification and androgen-regulated expression of two major human glandular kallikrein-1 (hGK-1) mRNA species". Mol. Cell. Endocrinol. 76 (1–3): 181–190. doi:10.1016/0303-7207(91)90272-T. PMID 1726490.
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Schedlich LJ, Bennetts BH, Morris BJ (1988). "Primary structure of a human glandular kallikrein gene". DNA. 6 (5): 429–437. doi:10.1089/dna.1987.6.429. PMID 2824146.
Frenette G, Deperthes D, Tremblay RR, et al. (1997). "Purification of enzymatically active kallikrein hK2 from human seminal plasma". Biochim. Biophys. Acta. 1334 (1): 109–15. doi:10.1016/s0304-4165(96)00080-3. PMID 9042371.
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Mikolajczyk SD, Millar LS, Kumar A, Saedi MS (1998). "Human glandular kallikrein, hK2, shows arginine-restricted specificity and forms complexes with plasma protease inhibitors". Prostate. 34 (1): 44–50. doi:10.1002/(SICI)1097-0045(19980101)34:1<44::AID-PROS6>3.0.CO;2-K. PMID 9428387.
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Mikolajczyk SD, Millar LS, Kumar A, Saedi MS (1999). "Prostatic human kallikrein 2 inactivates and complexes with plasminogen activator inhibitor-1". Int. J. Cancer. 81 (3): 438–442. doi:10.1002/(SICI)1097-0215(19990505)81:3<438::AID-IJC18>3.0.CO;2-U. PMID 10209959.
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Chen VC, Chao L, Chao J (2001). "A positively charged loop on the surface of kallistatin functions to enhance tissue kallikrein inhibition by acting as a secondary binding site for kallikrein". J. Biol. Chem. 275 (51): 40371–40377. doi:10.1074/jbc.M005691200. PMID 10991942.
Gan L, Lee I, Smith R, et al. (2001). "Sequencing and expression analysis of the serine protease gene cluster located in chromosome 19q13 region". Gene. 257 (1): 119–130. doi:10.1016/S0378-1119(00)00382-6. PMID 11054574.
Réhault S, Monget P, Mazerbourg S, et al. (2001). "Insulin-like growth factor binding proteins (IGFBPs) as potential physiological substrates for human kallikreins hK2 and hK3". Eur. J. Biochem. 268 (10): 2960–2968. doi:10.1046/j.1432-1327.2001.02185.x. PMID 11358513.
Saedi MS, Zhu Z, Marker K, et al. (2002). "Human kallikrein 2 (hK2), but not prostate-specific antigen (PSA), rapidly complexes with protease inhibitorستة (PI-6) released from prostate carcinoma cells". Int. J. Cancer. 94 (4): 558–563. doi:10.1002/ijc.1501. PMID 11745444.
تاريخ النشر:
2020-06-02 13:18:20
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